The MHTP Medical Genomics Facility is a not-for-profit facility whose mission focuses on the provision of innovative, cost-effective and readily accessible genomic services of the highest possible standard to support the medical research, clinical practice, and teaching requirements of MHTP partners as well as the wider scientific community.

The Facility is located at the Monash Health Translation Precinct, a partnership between the Hudson Institute, Monash Health and Monash University. The Precinct unites Victoria's biggest health provider and Australia's largest University with the Hudson Institute (the formerly Monash Institute of Medical Research and Prince Henry's Institute merged). This promotes cross-disciplinary interactions between medical researchers and clinicians, so that innovative discoveries in basic science can be readily translated in clinical practice and discovery research is informed by clinical need.

Located in Clayton, Victoria, the Facility is ideally located within the South East Melbourne Innovation Precinct (SEMIP), which hosts the Australian Synchrotron, CSIRO's largest Research and Development site and the Melbourne Centre of Nanofabrication. Researchers and clinicians have ready access to these powerful capabilities as well as those within complementary MHTP Technology Platforms and Monash Technology Research Platforms at Monash University.