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High Content Screening

High Content Screening (HCS) is the performance of quantitative, high-throughput cell-based assays that use automated image capture to measure changes in specific cellular processes. HCS enables researchers to perform cell biology experiments where cellular processes are detected by fluorescent dyes or antibodies

The Facility offers a range of High Content Screening services from instrument training through to performance of entire short interfering (si)RNA library screens. siRNA libraries enable researchers to individually 'knock-down' every gene in human or mouse genomes. The combination of siRNA libraries and automated high content imaging analysis enables unbiased, comprehensive analysis of the contribution of individual genes to cellular function.