History and Funding
Established in the Hudson Institute and located at the Monash Medical Centre in Clayton, Victoria, the MHTP Medical Genomics Facility services Monash Health Translation Precinct (MHTP) partners the Hudson Institute, Monash Health and Monash University, as well as the wider Victorian and National scientific community.
Formerly named the Wellcome Trust Sequencing Centre, our DNA Sequencing service arose as a result of a successful application in 1999 to the Wellcome Trust by researchers of the Hudson Institute. The Wellcome Trust supported purchase of an ABI PRISM 377 DNA sequencer.
In 2005, the Gandel Charitable Trust supported purchase of the AB 3130xl Genetic Analyser and the Centre was renamed the Gandel Charitable Trust Sequencing Centre to acknowledge the generosity of the Trust. Since then the Centre has been able to expand the Sanger Sequencing service and introduce complementary genomic services through the generosity of funding from government and philanthropic organisations:
Collier Charitable Trust 2008
Rebecca L Cooper Medical Research Foundation 2010
Gandel Philanthropy 2017
Australian Cancer Research Foundation
In 2010 the Australian Cancer Research Foundation (ACRF) generously provided $1.6M funding to establish a new Centre, the ACRF Centre for Cancer Genomic Medicine. This enabled the introduction of next generation sequencing technologies and complementary capabilities.
The primary objective of the ACRF Centre is the translation of patient cancer genomic data into the key decision-making processes during the use of cancer therapeutics to improve patient outcomes.
Australian Research Council and National Health and Medical Research Council
Grants led by researchers at the Hudson Institute, Monash University and collaborating organisations have been successful in advancing the Facility. This allowed purchase of High Content Screening and Single Cell Genomic technologies.
ARC Linkage Infrastructure, Equipment and Facilities (LIEF) grants 2008, 2014
NHMRC Equipment grants 2005, 2007, 2010, 2013
The Facility gratefully acknowledges financial and in-kind support from the Office of the Vice-Provost (Research and Research Infrastructure) Monash University.
MHTP Medical Genomics Facility
In 2010, the name MHTP Medical Genomics Facility was established to reflect the collective breadth of genomics capabilities available within each Centre.
The MHTP Medical Genomics Facility now hosts a comprehensive range of genomic technologies to support the multidisciplinary nature of medical research at the Hudson Institute, MHTP and nationally. Capabilities continue to advance - our latest introduction was Fluidigm Single Cell Genomics in 2014 for single cell and high throughput genomic analysis.